Issue launching apps

We are having an issue getting apps to launch out of desktop here is the following error:

  File "C:\Users\chris\AppData\Roaming\Shotgun\bundle_cache\app_store\tk-desktop\v2.5.13\python\tk_desktop\desktop_engine_site_implementation.py", line 355, in _handle_button_command_triggered
    "trigger_callback", "__commands", six.ensure_str(name)
  File "C:\Users\chris\AppData\Roaming\Shotgun\bundle_cache\app_store\tk-desktop\v2.5.13\python\tk_desktop\communication_base.py", line 97, in call_no_response
    return self._proxy.call_no_response(name, *args, **kwargs)
  File "C:\Users\chris\AppData\Roaming\Shotgun\bundle_cache\app_store\tk-desktop\v2.5.13\python\tk_desktop\rpc.py", line 408, in call_no_response
    self._connection.send(pickle.dumps((False, name, args, kwargs)))
  File "C:\Users\chris\AppData\Roaming\Shotgun\bundle_cache\app_store\tk-desktop\v2.5.13\python\tk_desktop\rpc.py", line 174, in send
    self._conn.send_bytes(payload)
IOError: [Errno 232] The pipe is being closed```