Hey, with the help of your guide, I am happy to report that we successfully created a subclass of the basic OCIO package, which loads our custom configs, sets spaces, etc.
We ended up baking a lookup file at “compile time” to avoid Shotgun requests, since RV is expected to be fast, apparently 
We haven’t got around to per-shot context variables yet, since it becomes more difficult to avoid querying Shotgun.
The next hangup we’re having is that the Channel Display options (bound to a r g b) do not work. It appears they are relying on the built-in color pipeline (in rvui.mu), or I might be interpreting it wrong.
Cheers,
Mois